The Connection Between Methylation and Aging Is Gaining Traction 

What possible connections could Methylation and aging actually have, and what the heck is it?

This connection, just 10 years ago was not very well known nor was it all that concerning, however, in just a few short years it has moved to the forefront of dangerous conditions. 

In fact, improving this process will not only improve our lives, it could possibly save them in a lot of cases.

Aging and DNA Methylation Connection to Diseases

The connection with Methylation and aging is gaining a lot of momentum, especially in the last five years for several reasons, but perhaps the following is the most important.

It turns our genes on and off.

While most of us past the age of 55 most likely have never heard the term, once you begin to understand what it can do for us, it becomes extremely interesting.

However, what it does not do for us should be not only very interesting; it should be both worrisome as well as frightening.

In fact, this condition is not just as dangerous as inflammation and aging, in some cases, it is a lot more dangerous.

Methylation and Aging

It is linked to at least 100 different diseases and conditions as we age, and here is just a sampling of some of them.

  • Cancer-now emerging as perhaps the leading cause
  • Chronic fatigue syndrome as well as Fibromyalgia
  • It can very easily lead to several types of additive behaviors
  • Insomnia and other sleeping disorders
  • Allergies and other chemical sensations
  • Depression, as well as manic depression.

Because most of us have never heard about it or fully understood it, it can be quite complicated.

However, it is easy to understand if explained this way.

It turns our genes on and off by adding a single form of carbon, as well as three atoms made up of hydrogen to a single molecule.

The three atoms of hydrogen and referred to as the “methyl group”, and this is where it gets its name.

Once We Hit 55 They Become Critical

Once this “methyl group” has been removed, it is referred to as “demethylation” and this is best described as literally billions of minuet “on and off” switches that do several key functions.

These functions are important to us in all stages of life, but as we pass that magic age of 55, they become critical.

This is where the connection with Methylation and aging really begins to emerge, as it helps our brain chemistry, the detoxification process, as well as making energy for our body.

However, it also helps repair our DNA, fights infections, and is the controlling force with how our genes are turned on and off.

In the world of medicine the term is referred to not as the link that turns our genes on and off, instead, it is referred to it as “genetic defects”.

Once our DNA, (our genetic code), becomes affected several bad things can happen and here are more of the diseases and conditions this process is linked to.

  • Schizophrenia as well as Dementia
  • Alzheimer’s disease
  • Severe Lyme disease which is very dangerous
  • Several forms of chronic infection
  • Diabetes

While these two lists are far from being all inclusive, they are some of the most dangerous.

Three Friends Enjoying Time TogetherThree Friends Enjoying Time Together

Methylation and aging also plays a major role in both making as well as breaking down several forms of neurotransmitters, and this makes the connection even stronger.

While most of us have heard about the benefits of producing neurotransmitters for the majority of our mental and brain functions, we may have not heard about the other threat.

If we are unable to break them down properly, the medical community in the last 10 years has linked this as one of the most prevalent causes of strokes.

The chemical melatonin is one of the key factors for us being able to sleep properly, especially as we age, and it is affected as well by this process.

It also effects “epinephrine” which is a fundamental agent is our ability to make energy for our bodies.

However, perhaps the worst thing it may do to our body when it is not operating properly is to affect our “Glutathione levels”.

Glutathione is one of the simple molecules that can be affected with Methylation and aging, and while it is naturally produced by our body, it can and is affected by this process.

45 % Of Us Have This Defect

So why exactly is this simple molecule so important?

It is not only a very strong detoxifier, it is considered to be the “major antioxidant” in our entire immune system.

Once it becomes challenged, all kinds of bad things can and do start to happen.

However, here is perhaps the single biggest concern with Methylation and aging; 45% of all people have this “genetic defect”, and as we get older, it climbs ever higher.

The news is not all bad, however, and it centers on what is referred to as “methylfolate”.

This is the most active form of the nutrient folate in our body, and it is found abundantly in the following nutrients.

They include the following.

  • The mineral zinc and magnesium
  • Two B vitamins that include B2, riboflavin, and B12  “methylcobalamin”
  • Folic acid

In your diet is not supplying enough of these nutrients naturally, you may need to supplement them

Be Careful With B-12

Vitamin B12 is perhaps the strongest of all the nutrients that help with our neurotransmitters, but there is a word of caution about this nutrient.

Although it is a water soluble vitamin, it is stored in our liver.

From personal experience with my wife, if you supplement it, only take one per day, as 2 can be stored and may cause liver damage.

Some medications as well as OTC medications can deplete your body of these nutrients, and as we age, this is the last thing we want.

We need it to be able to turn our genes off and on the way they were designed to do, and here are some medications that can affect this process.

They include the following.

  • Antacids in any form
  • Methotrexate used for Psoriasis and Rheumatoid Arthritis
  • Corticosteroids 

Some personal habits and unneeded pressure can also increase the chances of damage, if you do not take the needed precautions.

If you drink alcohol, it will rapidly deplete most of these nutrients, and Green coffee beans are even worse for us as we age.

Slo-Niacin also depletes them as can chronic Anxiety and Stress.


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